Liverpool are said to be 'concerned' that Alexander Isak sustained 'significant' damage to his leg after being hauled off injured during Saturday's 2-1 win at Tottenham. Isak broke the deadlock with a strike shortly after the half-time break, but was brought down by Spurs defender Micky van de Ven in the process, with the Dutchman sliding into the Swede at full pace, trapping the striker's leg in an awkward position.Isak was introduced as a substitute at the start of the second half in place of Conor Bradley, with Liverpool boss Arne Slot seemingly keen to add more firepower to his side with the scores locked at 0-0 but with Tottenham a man light after Xavi Simons was sent off for a late challenge on Virgil van Dijk.Within ten minutes of his introduction, Isak's name was on the scoresheet, but instead of running off to celebrate his goal, he writhed in pain on the floor and immediately called for medical assistance. After several minutes of treatment, he hobbled off and was replaced by Jeremie Frimpong.As first reported by The Athletic, Liverpool believe the extent of Isak's leg injury is 'significant' and are 'concerned' at the damage he has sustained. The striker is yet to undergo an MRI scan which will reveal how long he may be sidelined for, but initial signs are not promising.Looking for smarter football bets? Get expert previews, data-driven predictions & winning insights with GOAL Tips on Telegram. Join our growing community now!Slot was asked about Isak at his post-match press conference, to which he replied: "I don't have any news on him. But if a player scores and then gets injured, and doesn't come back on the pitch, doesn't try to come back - which is what Conor Bradley tried to do for example but I had to take him off as well because he couldn't go on. But if a player doesn't even try to come back, that is usually not a good thing. But I cannot say anything more than that, it is just a gut feeling. Nothing medical to say about it. I haven't spoken to him about it yet."Add GOAL.com as a preferred source on Google to see more of our reportingIsak's goal at Tottenham was just his second in the Premier League since his £125 million ($166m) move from Newcastle on deadline day of the summer transfer window, with his only other strike coming in a 1-0 win at West Ham on November 30.The Swede has been rotated in and out of Slot's starting lineup all season long, with fellow summer arrival Hugo Ekitike splitting the minutes as the No.9. Unlike Isak, Ekitike has proven a hit at Anfield so far, scoring 10 times for Liverpool in all competitions already. He scored the Reds' second against Spurs, rising above Cristian Romero to head home a deflected cross from Frimpong.Star forward Mohamed Salah is currently at the Africa Cup of Nations with Egypt, while there is increasing speculation that Harvey Elliott could return to the club in January having failed to make an impact on loan at Aston Villa.